产品名称
RDH5 Rabbit Polyclonal Antibody
蛋白名称
11-cis retinol dehydrogenase (11-cis RDH) (11-cis RoDH) (EC 1.1.1.315) (9-cis retinol dehydrogenase) (9cRDH)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5959
Human Swissprot No.
Q92781
Human Swissprot Link
https://www.uniprot.org/uniprot/Q92781
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19682
Mouse Swissprot No.
O55240
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O55240/entry
特异性
This antibody detects endogenous levels of RDH5 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed. In the eye, abundant in the retinal pigment epithelium.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein ; Lumenal side .
功能
Catalyzes the oxidation of cis-isomers of retinol, including 11-cis-, 9-cis-, and 13-cis-retinol in an NAD-dependent manner . Has no activity towards all-trans retinal (By similarity). Plays a significant role in 11-cis retinol oxidation in the retinal pigment epithelium cells (RPE). Also recognizes steroids (androsterone, androstanediol) as its substrates .
