产品名称
RAI1 Rabbit Polyclonal Antibody
蛋白名称
Retinoic acid-induced protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10743
Human Swissprot No.
Q7Z5J4
Human Swissprot Link
https://www.uniprot.org/uniprot/Q7Z5J4
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19377
Mouse Swissprot No.
Q61818
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q61818/entry
特异性
This antibody detects endogenous levels of RAI1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in all tissues examined with higher expression in the heart and brain. No expression was seen in the corpus callosum of the brain.
细胞定位
Cytoplasm. Nucleus. In neurons, localized to neurites. .
功能
Transcriptional regulator of the circadian clock components: CLOCK, ARNTL/BMAL1, ARNTL2/BMAL2, PER1/3, CRY1/2, NR1D1/2 and RORA/C. Positively regulates the transcriptional activity of CLOCK a core component of the circadian clock. Regulates transcription through chromatin remodeling by interacting with other proteins in chromatin as well as proteins in the basic transcriptional machinery. May be important for embryonic and postnatal development. May be involved in neuronal differentiation.
