产品名称
IER3IP1 Rabbit Polyclonal Antibody
蛋白名称
Immediate early response 3-interacting protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51124
Human Swissprot No.
Q9Y5U9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y5U9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66191
Mouse Swissprot No.
Q9CR20
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CR20/entry
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P85007/entry
特异性
This antibody detects endogenous levels of IER3IP1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highest levels in heart, skeletal muscle, and kidney.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
Regulator of endoplasmic reticulum secretion that acts as a key determinant of brain size . Required for secretion of extracellular matrix proteins . Required for correct brain development by depositing sufficient extracellular matrix proteins for tissue integrity and the proliferation of neural progenitors . Acts as a regulator of the unfolded protein response (UPR) (By similarity).
