产品名称
HPSE2 Rabbit Polyclonal Antibody
蛋白名称
Inactive heparanase-2 (Hpa2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=60495
Human Swissprot No.
Q8WWQ2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8WWQ2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=545291
Mouse Swissprot No.
B2RY83
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/B2RY83/entry
特异性
This antibody detects endogenous levels of HPSE2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed, with the highest expression in brain, mammary gland, prostate, small intestine, testis and uterus. In the central nervous system, expressed in the spinal chord, caudate nucleus, thalamus, substantia nigra, medulla oblongata, putamen and pons. In the urinary bladder, expressed in longitudinal and circular layers of detrusor muscle. Found both in normal and cancer tissues.
细胞定位
Secreted, extracellular space, extracellular matrix .
功能
Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro).
