产品名称
GLYAT Rabbit Polyclonal Antibody
基因名称
GLYAT ACGNAT CAT GAT
蛋白名称
Glycine N-acyltransferase (EC 2.3.1.13) (EC 2.3.1.71) (Acyl-CoA:glycine N-acyltransferase) (AAc) (Aralkyl acyl-CoA N-acyltransferase) (Aralkyl acyl-CoA:amino acid N-acyltransferase) (Benzoyl-coenzyme A:glycine N-acyltransferase) (Glycine N-benzoyltransferase) (HRP-1(CLP))
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10249
Human Swissprot No.
Q6IB77
Human Swissprot Link
https://www.uniprot.org/uniprot/Q6IB77
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=107146
Mouse Swissprot No.
Q91XE0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91XE0/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=293779
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5PQT3/entry
特异性
This antibody detects endogenous levels of GLYAT at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers.
功能
Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.