产品名称
DTNB Rabbit Polyclonal Antibody
蛋白名称
Dystrobrevin beta (DTN-B) (Beta-dystrobrevin)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1838
Human Swissprot No.
O60941
Human Swissprot Link
https://www.uniprot.org/uniprot/O60941
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13528
Mouse Swissprot No.
O70585
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O70585/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=362715
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P84060/entry
特异性
This antibody detects endogenous levels of DTNB at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in brain, kidney and pancreas.
细胞定位
Cytoplasm . Cell junction, synapse, postsynaptic density . Cell projection, dendrite . Basal cell membrane . Cell junction, synapse, postsynapse . Nucleus . Localized at inhibitory synapses on the dendrites of cerebellar Purkinje cells. .
功能
Scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids (By similarity). May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation . May be required for proper maturation and function of a subset of inhibitory synapses (By similarity).
