产品名称
C2orf60 Rabbit Polyclonal Antibody
蛋白名称
tRNA wybutosine-synthesizing protein 5 (hTYW5) (EC 1.14.11.-)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=129450
Human Swissprot No.
A2RUC4
Human Swissprot Link
https://www.uniprot.org/uniprot/A2RUC4
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=68736
Mouse Swissprot No.
A2RSX7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/A2RSX7/entry
特异性
This antibody detects endogenous levels of C2orf60 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes.
