产品名称
CCL1 Rabbit Polyclonal Antibody
蛋白名称
C-C motif chemokine 1 (Small-inducible cytokine A1) (T lymphocyte-secreted protein I-309)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P22362
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P22362/entry
Mouse Swissprot No.
P10146
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P10146
免疫原
Synthesized peptide derived from human protein . at AA range: 20-100
特异性
CCL1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014],
信号通路
Cytokine-cytokine receptor interaction;Chemokine;
功能
function:Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.,induction:By PMA.,online information:CCL1 entry,similarity:Belongs to the intercrine beta (chemokine CC) family.,subunit:Monomer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.