产品名称
S6A20 Rabbit Polyclonal Antibody
基因名称
SLC6A20 SIT1 XT3 XTRP3
蛋白名称
Sodium- and chloride-dependent transporter XTRP3 (Sodium/imino-acid transporter 1) (Solute carrier family 6 member 20) (Transporter rB21A homolog)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NP91
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NP91/entry
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q64093
免疫原
Synthesized peptide derived from part region of human protein
特异性
S6A20 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Transport of small hydrophilic substances across cell membranes is mediated by substrate-specific transporter proteins which have been classified into several families of related genes. The protein encoded by this gene is a member of the subgroup of transporter with unidentified substrates within the Na+ and Cl- coupled transporter family. This gene is expressed in kidney, and its alternative splicing generates 2 transcript variants. [provided by RefSeq, Jul 2008],
组织表达
Kidney and small intestine. Expressed in the S3 segment of the proximal tubule.
细胞定位
Apical cell membrane ; Multi-pass membrane protein . Located in the apical brush border membrane of kidney proximal tubule cells. .
功能
function:Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N-methylated amino acids.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,subcellular location:Located in the apical brush border membrane of kidney proximal tubule cells.,tissue specificity:Kidney and small intestine.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
