产品名称
PTBP3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9991
Human Swissprot No.
O95758
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O95758/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/230257
Mouse Swissprot No.
Q8BHD7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BHD7
Rat Gene Link
https://www.uniprot.org/uniprot/83515
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z118
免疫原
Synthesized peptide derived from human PTBP3 AA range: 103-153
特异性
This antibody detects endogenous levels of PTBP3 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
组织表达
Expressed in several hematopoietic cell lines examined.
功能
function:May play a role in regulation of differentiation. In vitro, binds RNA, preferentially to both poly(G) and poly(U). Overexpressed, blocks differentiation of K562 leukemia cells following treatment with phorbol esters or sodium butyrate without affecting proliferation.,similarity:Contains 4 RRM (RNA recognition motif) domains.,tissue specificity:Expressed in several hematopoietic cell lines examined.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
