产品名称
SSA27 Rabbit Polyclonal Antibody
蛋白名称
Sjoegren syndrome/scleroderma autoantigen 1 (Autoantigen p27)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O60232
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O60232/entry
Mouse Swissprot No.
P56873
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P56873
免疫原
Synthesized peptide derived from part region of human protein
特异性
SSA27 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This antigen is recognized by a subset of anti-centromere antibodies from patients with scleroderma and/or Sjogren's syndrome. Subcellular localization has not yet been established. [provided by RefSeq, Jul 2008],
功能
function:Might play a role in mitosis. Antigenic molecule. Could be a centromere-associated protein. May induce anti-centromere antibodies.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.