产品名称
PUF-A,KIAA0020 Rabbit Polyclonal Antibody
蛋白名称
Pumilio domain-containing protein KIAA0020 (HBV X-transactivated gene 5 protein) (HBV XAg-transactivated protein 5) (Minor histocompatibility antigen HA-8) (HLA-HA8)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9933
Human Swissprot No.
Q15397
Human Swissprot Link
https://www.uniprot.org/uniprot/Q15397
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=52874
Mouse Swissprot No.
Q8BKS9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BKS9/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=499339
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q562C7/entry
特异性
This antibody detects endogenous levels of PUF-A,KIAA0020 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus, nucleolus . Nucleus, nucleoplasm . Chromosome . Localizes predominantly in the nucleolus with minor punctate signals in the nucleoplasm. .
功能
Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress . Binds to double-stranded RNA or DNA without sequence specificity . Involved in development of the eye and of primordial germ cells (By similarity).
