产品名称
SGSM1 Rabbit Polyclonal Antibody
基因名称
SGSM1 KIAA1941 RUTBC2
蛋白名称
Small G protein signaling modulator 1 (RUN and TBC1 domain-containing protein 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=129049
Human Swissprot No.
Q2NKQ1
Human Swissprot Link
https://www.uniprot.org/uniprot/Q2NKQ1
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=52850
Mouse Swissprot No.
Q8BPQ7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BPQ7/entry
特异性
This antibody detects endogenous levels of SGSM1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Mainly expressed in brain, heart and testis.
细胞定位
Golgi apparatus, trans-Golgi network . Cytoplasmic vesicle membrane ; Peripheral membrane protein . Cytoplasm . Recruited to cytoplasmic vesicle membranes via its interaction with Rab family members, such as RAB9A. .
功能
Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B.