产品名称
SRP54 Rabbit Polyclonal Antibody
蛋白名称
Signal recognition particle 54 kDa protein (SRP54)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P61011
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P61011/entry
Mouse Swissprot No.
P14576
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P14576
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q6AYB5
免疫原
Synthesized peptide derived from part region of human protein
特异性
SRP54 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
domain:Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.,function:Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).,online information:Signal recognition particle entry,similarity:Belongs to the GTP-binding SRP family.,subunit:Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. Interacts with RNPS1.,
组织表达
Eye,Placenta,Trachea,
细胞定位
Nucleus speckle . Cytoplasm . Endoplasmic reticulum .
功能
domain:Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.,function:Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).,online information:Signal recognition particle entry,similarity:Belongs to the GTP-binding SRP family.,subunit:Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. Interacts with RNPS1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.