产品名称
ASGR2 Rabbit Polyclonal Antibody
蛋白名称
Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (C-type lectin domain family 4 member H2) (Hepatic lectin H2) (HL-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=433
Human Swissprot No.
P07307
Human Swissprot Link
https://www.uniprot.org/uniprot/P07307
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11890
Mouse Swissprot No.
P24721
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P24721/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29403
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P08290/entry
特异性
This antibody detects endogenous levels of ASGR2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed exclusively in hepatic parenchymal cells.
细胞定位
Membrane; Single-pass type II membrane protein.
功能
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
