产品名称
TDRD5 Rabbit Polyclonal Antibody
蛋白名称
Tudor domain-containing protein 5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=163589
Human Swissprot No.
Q8NAT2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8NAT2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=214575
Mouse Swissprot No.
Q5VCS6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q5VCS6/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=289129
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/B4F7C4/entry
特异性
This antibody detects endogenous levels of TDRD5 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis. .
功能
Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity).
