产品名称
STXBP5 Rabbit Polyclonal Antibody
蛋白名称
Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=134957
Human Swissprot No.
Q5T5C0
Human Swissprot Link
https://www.uniprot.org/uniprot/Q5T5C0
Mouse Swissprot No.
Q8K400
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K400/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81022
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WU70/entry
特异性
This antibody detects endogenous levels of STXBP5 at Human,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Cell membrane ; Peripheral membrane protein . Cytoplasmic vesicle membrane ; Peripheral membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle . Cell junction, synapse . Cytoplasmic, and associated with vesicular membranes and the plasma membrane. Detected at synapses and on synaptic vesicles (By similarity). .
功能
Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Competes with STXBP1 for STX1 binding (By similarity).
