产品名称
SEC14L1 Rabbit Polyclonal Antibody
蛋白名称
SEC14-like protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6397
Human Swissprot No.
Q92503
Human Swissprot Link
https://www.uniprot.org/uniprot/Q92503
特异性
This antibody detects endogenous levels of SEC14L1 at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Golgi apparatus .
功能
May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation . May also regulate the SLC18A3 and SLC5A7 cholinergic transporters .