产品名称
DIS3L Rabbit Polyclonal Antibody
基因名称
DIS3L DIS3L1 KIAA1955
蛋白名称
DIS3-like exonuclease 1 (EC 3.1.13.-)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=115752
Human Swissprot No.
Q8TF46
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8TF46
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=213550
Mouse Swissprot No.
Q8C0S1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8C0S1/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=363077
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5U2P0/entry
特异性
This antibody detects endogenous levels of DIS3L at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.
