产品名称
C10orf58 Rabbit Polyclonal Antibody
基因名称
FAM213A C10orf58 PAMM PRO2290 PSEC0139 UNQ611/PRO1198
蛋白名称
Redox-regulatory protein FAM213A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84293
Human Swissprot No.
Q9BRX8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9BRX8
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70564
Mouse Swissprot No.
Q9CYH2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CYH2/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=361118
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6AXX6/entry
特异性
This antibody detects endogenous levels of C10orf58 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in CSF1 and TNFSF11-stimulated CD14(+) peripheral blood mononuclear cells (PBMCs).
细胞定位
Cytoplasm . Secreted . Secreted from mature adipocytes but not from preadipocytes. .
功能
Involved in redox regulation of the cell . Acts as an antioxidant . Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation . May affect bone resorption and help to maintain bone mass . Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway .
