产品名称
UFM1 Rabbit Polyclonal Antibody
基因名称
UFM1 C13orf20 BM-002
蛋白名称
Ubiquitin-fold modifier 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51569
Human Swissprot No.
P61960
Human Swissprot Link
https://www.uniprot.org/uniprot/P61960
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67890
Mouse Swissprot No.
P61961
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P61961/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=365797
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5BJP3/entry
特异性
This antibody detects endogenous levels of UFM1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus . Cytoplasm .
功能
Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer . The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 . Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress . Ufmylation of TRIP4 regulates nuclear receptors-mediated transcription .
