产品名称
FBXL15 Rabbit Polyclonal Antibody
蛋白名称
F-box/LRR-repeat protein 15 (F-box only protein 37)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79176
Human Swissprot No.
Q9H469
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H469
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=68431
Mouse Swissprot No.
Q91W61
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91W61/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=309453
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/D4ABB4/entry
特异性
This antibody detects endogenous levels of FBXL15 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.
