产品名称
ZGLP1 Rabbit Polyclonal Antibody
蛋白名称
GATA-type zinc finger protein 1 (GATA-like protein 1) (GLP-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100125288
Human Swissprot No.
P0C6A0
Human Swissprot Link
https://www.uniprot.org/uniprot/P0C6A0
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100009600
Mouse Swissprot No.
Q1WG82
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q1WG82/entry
特异性
This antibody detects endogenous levels of ZGLP1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Transcriptional regulator that plays a key role in germ cell development. Determines the oogenic fate by activating key genes for the oogenic program and meiotic prophase entry. Acts downstream of bone morphogenetic protein (BMP) by regulating expression of genes required for the oogenic programs, which are repressed by Polycomb activities in sexually uncommitted germ cells. Regulates expression of STRA8, a central downstream effector for the meiotic program. Acts independently of retinoic acid (RA). In males, not required for germ-cell sex determination, but required to allow the spermatogonia to efficiently accomplish the meiotic prophase.
