产品名称
SPACA3 Rabbit Polyclonal Antibody
基因名称
SPACA3 LYC3 LYZL3 SLLP1 SPRASA UNQ424/PRO862
蛋白名称
Sperm acrosome membrane-associated protein 3 (Cancer/testis antigen 54) (CT54) (Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17) (Lysozyme-like protein 3) (Sperm lysozyme-like protein 1) (Sperm protein reactive with antisperm antibodies) (Sperm protein reactive with ASA) [Cleaved into: Sperm acrosome membrane-associated protein 3, membrane form; Sperm acrosome membrane-associated protein 3, processed form]
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=124912
Human Swissprot No.
Q8IXA5
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8IXA5
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=75622
Mouse Swissprot No.
Q9D9X8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D9X8/entry
特异性
This antibody detects endogenous levels of SPACA3 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
The processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta.
细胞定位
[Isoform 1]: Cytoplasmic vesicle, secretory vesicle, acrosome membrane ; Single-pass type II membrane protein . Anterior acrosome in non-capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction. .; [Isoform 2]: Secreted .
功能
Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
