产品名称
WDR74 Rabbit Polyclonal Antibody
蛋白名称
WD repeat-containing protein 74 (NOP seven-associated protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54663
Human Swissprot No.
Q6RFH5
Human Swissprot Link
https://www.uniprot.org/uniprot/Q6RFH5
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=107071
Mouse Swissprot No.
Q8VCG3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VCG3/entry
特异性
This antibody detects endogenous levels of WDR74 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus, nucleolus . Nucleus . Nucleolar location depends on active PolI transcription of pre-rRNA. .
功能
Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit . Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL . Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development (By similarity).
