产品名称
TMEM27 Rabbit Polyclonal Antibody
基因名称
TMEM27 UNQ679/PRO1312
蛋白名称
Collectrin (Transmembrane protein 27)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57393
Human Swissprot No.
Q9HBJ8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9HBJ8
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57394
Mouse Swissprot No.
Q9ESG4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9ESG4/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57395
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9ESG3/entry
特异性
This antibody detects endogenous levels of TMEM27 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Kidney; collecting ducts. Pancreas; beta cells of islets.
细胞定位
Cell membrane ; Single-pass type I membrane protein . Localizes to the brush border membranes of cells in the proximal tubules of kidney (By similarity). Colocalizes with SLC6A19 in the early proximal S1 tubule (By similarity). .
功能
Plays an important role in amino acid transport by acting as binding partner of amino acid transporters SLC6A18 and SLC6A19, regulating their trafficking on the cell surface and their amino acid transporter activity (By similarity). May also play a role in trafficking of amino acid transporters SLC3A1 and SLC7A9 to the renal cortical cell membrane (By similarity). Regulator of SNARE complex function . Stimulator of beta cell replication .
