产品名称
LST1 Rabbit Polyclonal Antibody
蛋白名称
Leukocyte-specific transcript 1 protein (Protein B144)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7940
Human Swissprot No.
O00453
Human Swissprot Link
https://www.uniprot.org/uniprot/O00453
Mouse Swissprot No.
O08843
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O08843/entry
特异性
This antibody detects endogenous levels of LST1 at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in lung, tonsil, thymus, placenta, kidney, fetal spleen, fetal liver and brain.
细胞定位
Membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm.
功能
Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.
