产品名称
IMPAD1 Rabbit Polyclonal Antibody
蛋白名称
Inositol monophosphatase 3 (IMP 3) (IMPase 3) (EC 3.1.3.25) (EC 3.1.3.7) (Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase) (Golgi-resident PAP phosphatase) (gPAPP) (Inositol monophosphatase domain-containing protein 1) (Inositol-1(or 4)-monophosphatase 3) (Myo-inositol monophosphatase A3)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54928
Human Swissprot No.
Q9NX62
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NX62
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=242291
Mouse Swissprot No.
Q80V26
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80V26/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100910881
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/D4AD37/entry
特异性
This antibody detects endogenous levels of IMPAD1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Golgi apparatus . Golgi apparatus, trans-Golgi network membrane ; Single-pass type II membrane protein . The catalytic core is predicted to reside within the Golgi lumen. .
功能
Exhibits 3'-nucleotidase activity toward adenosine 3',5'-bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, I(1,3,4)P3, I(1,4,5)P3 and I(1,3,4,5)P4.
