产品名称
HIST1H2AC Rabbit Polyclonal Antibody
蛋白名称
Histone H2A type 1-C (Histone H2A/l)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8334
Human Swissprot No.
Q93077
Human Swissprot Link
https://www.uniprot.org/uniprot/Q93077
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P0C169/entry
特异性
This antibody detects endogenous levels of HIST1H2AC at Human,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus. Chromosome.
功能
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.