产品名称
FLJ14213 Rabbit Polyclonal Antibody
蛋白名称
Proline-rich protein 5-like (Protein observed with Rictor-2) (Protor-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79899
Human Swissprot No.
Q6MZQ0
Human Swissprot Link
https://www.uniprot.org/uniprot/Q6MZQ0
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=72446
Mouse Swissprot No.
A2AVJ5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/A2AVJ5/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=362171
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/A1L1K1/entry
特异性
This antibody detects endogenous levels of FLJ14213 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Associates with the mTORC2 complex that regulates cellular processes including survival and organization of the cytoskeleton . Regulates the activity of the mTORC2 complex in a substrate-specific manner preventing for instance the specific phosphorylation of PKCs and thereby controlling cell migration . Plays a role in the stimulation of ZFP36-mediated mRNA decay of several ZFP36-associated mRNAs, such as TNF-alpha and GM-CSF, in response to stress . Required for ZFP36 localization to cytoplasmic stress granule (SG) and P-body (PB) in response to stress .
