产品名称
C1orf86 Rabbit Polyclonal Antibody
基因名称
FAAP20 C1orf86 FP7162
蛋白名称
Fanconi anemia-associated protein of 20 kDa
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=199990
Human Swissprot No.
Q6NZ36
Human Swissprot Link
https://www.uniprot.org/uniprot/Q6NZ36
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67513
Mouse Swissprot No.
Q3UN58
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3UN58/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=362678
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/D4AAA5/entry
特异性
This antibody detects endogenous levels of C1orf86 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus . Chromosome . Following DNA damage, recruited to DNA interstrand cross-links (ICLs) sites by binding to ubiquitin generated by RNF8. .
功能
Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1.
