产品名称
ANKRD13A Rabbit Polyclonal Antibody
蛋白名称
Ankyrin repeat domain-containing protein 13A (Protein KE03)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=88455
Human Swissprot No.
Q8IZ07
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8IZ07
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=68420
Mouse Swissprot No.
Q80UP5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80UP5/entry
特异性
This antibody detects endogenous levels of ANKRD13A at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cell membrane . Late endosome . Interaction with EGFR may enhance association with the cell membrane.
功能
Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
