产品名称
OTUD6B Rabbit Polyclonal Antibody
蛋白名称
OTU domain-containing protein 6B (DUBA-5)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51633
Human Swissprot No.
Q8N6M0
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8N6M0
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=72201
Mouse Swissprot No.
Q8K2H2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K2H2/entry
特异性
This antibody detects endogenous levels of OTUD6B at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
[Isoform 1]: Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of protein synthesis, downstream of mTORC1 . May associate with the protein synthesis initiation complex and modify its ubiquitination to repress translation . May also repress DNA synthesis and modify different cellular targets thereby regulating cell growth and proliferation . May also play a role in proteasome assembly and function . ; [Isoform 2]: Stimulates protein synthesis. Influences the expression of CCND1/cyclin D1 by promoting its translation and regulates MYC/c-Myc protein stability.
