产品名称
KCC4/SLC12A7 Rabbit Polyclonal Antibody
蛋白名称
Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10723
Human Swissprot No.
Q9Y666
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y666
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20499
Mouse Swissprot No.
Q9WVL3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WVL3/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=308069
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5RK27/entry
特异性
This antibody detects endogenous levels of KCC4/SLC12A7 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Detected in muscle, brain, lung, heart and kidney.
细胞定位
Cell membrane; Multi-pass membrane protein.
功能
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity).
