产品名称
FEZ1 Rabbit Polyclonal Antibody
蛋白名称
Fasciculation and elongation protein zeta-1 (Zygin I) (Zygin-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9638
Human Swissprot No.
Q99689
Human Swissprot Link
https://www.uniprot.org/uniprot/Q99689
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=235180
Mouse Swissprot No.
Q8K0X8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K0X8/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81730
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P97577/entry
特异性
This antibody detects endogenous levels of FEZ1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Mainly expressed in brain.
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell membrane . Colocalizes with both, alpha- and gamma-tubulin. Translocated from the plasma membrane to the cytoplasm by activation of the PKC zeta (By similarity). .
功能
May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules.
