产品名称
TMEM65 Rabbit Polyclonal Antibody
蛋白名称
Transmembrane protein 65
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=157378
Human Swissprot No.
Q6PI78
Human Swissprot Link
https://www.uniprot.org/uniprot/Q6PI78
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=74868
Mouse Swissprot No.
Q4VAE3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q4VAE3/entry
特异性
This antibody detects endogenous levels of TMEM65 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Predominantly expressed the ventricular tissue (at protein level).
细胞定位
Cell membrane ; Multi-pass membrane protein . Mitochondrion inner membrane ; Multi-pass membrane protein . Localizes at the intercalated disk in the ventricular tissue (PubMed:26403541). .
功能
May play an important role in cardiac development and function. May regulate cardiac conduction and the function of the gap junction protein GJA1. May contribute to the stability and proper localization of GJA1 to cardiac intercalated disk thereby regulating gap junction communication (By similarity). May also play a role in the regulation of mitochondrial respiration and mitochondrial DNA copy number maintenance .
