产品名称
GULP1 Rabbit Polyclonal Antibody
蛋白名称
PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51454
Human Swissprot No.
Q9UBP9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9UBP9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70676
Mouse Swissprot No.
Q8K2A1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K2A1/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=314543
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5PQS4/entry
特异性
This antibody detects endogenous levels of GULP1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary.
细胞定位
Cytoplasm . May associate with the cytoplasmic side of the plasma membrane and early endosomes.
功能
May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
