产品名称
WBP11 Rabbit Polyclonal Antibody
基因名称
WBP11 NPWBP SIPP1 SNP70
蛋白名称
WW domain-binding protein 11 (WBP-11) (Npw38-binding protein) (NpwBP) (SH3 domain-binding protein SNP70) (Splicing factor that interacts with PQBP-1 and PP1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51729
Human Swissprot No.
Q9Y2W2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y2W2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=60321
Mouse Swissprot No.
Q923D5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q923D5/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100910115
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5PQQ2/entry
特异性
This antibody detects endogenous levels of WBP11 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Ubiquitous. Highly expressed in the heart, pancreas, kidney skeletal muscle, placenta and brain (at protein level). Weakly expressed in liver and lung.
细胞定位
Nucleus. Cytoplasm. Predominantly located in the nucleus with granular heterogeneous distribution. Excluded from nucleoli in interphase cells, distributed throughout cytoplasm in dividing cells. Colocalized with SC35 and U2B in the nucleus. In the cytoplasm, associates with the intermediate filament protein vimentin.
功能
Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity.
