产品名称
AP3S2 Rabbit Polyclonal Antibody
蛋白名称
AP-3 complex subunit sigma-2 (AP-3 complex subunit sigma-3B) (Adapter-related protein complex 3 sigma-2 subunit) (Sigma-3B-adaptin) (Sigma3B-adaptin) (Sigma-adaptin 3b)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10239
Human Swissprot No.
P59780
Human Swissprot Link
https://www.uniprot.org/uniprot/P59780
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11778
Mouse Swissprot No.
Q8BSZ2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BSZ2/entry
特异性
This antibody detects endogenous levels of AP3S2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Present in all adult tissues examined.
细胞定位
Golgi apparatus. Cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. .
功能
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
