产品名称
UNC45B Rabbit Polyclonal Antibody
蛋白名称
Protein unc-45 homolog B (Unc-45B) (SMUNC45)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=146862
Human Swissprot No.
Q8IWX7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8IWX7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=217012
Mouse Swissprot No.
Q8CGY6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8CGY6/entry
特异性
This antibody detects endogenous levels of UNC45B at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in eye lens tissues. Expressed in muscle (at protein level) (PubMed:33217308).
细胞定位
Cytoplasm, myofibril, sarcomere, Z line . Cytoplasm, myofibril, sarcomere, A band . Cytoplasm, perinuclear region . Cytoplasm, cytosol . Expressed at the Z line and in the perinuclear region of myofibrils. Translocates to the A band in response to stress conditions and fibril damage. .
功能
Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development.
