产品名称
SPB10 Rabbit Polyclonal Antibody
蛋白名称
Serpin B10 (Bomapin) (Peptidase inhibitor 10) (PI-10)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P48595
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P48595/entry
Mouse Swissprot No.
Q8K1K6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K1K6
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q8K3K4
免疫原
Synthesized peptide derived from part region of human protein
特异性
SPB10 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the serpin peptidase inhibitor, clade B family and is found in a cluster of other similar genes on chromosome 18. The protein encoded by this gene appears to help control the regulation of protease functions during hematopoiesis. Variations in this gene may increase the risk of prostate cancer. [provided by RefSeq, Dec 2015],
组织表达
Expressed specifically in myeloid cells and the bone marrow.
细胞定位
Nucleus. Cytoplasm. Mostly found in the nucleus.
功能
function:Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Expressed specifically in the bone marrow.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.