产品名称
TPM2 Rabbit Polyclonal Antibody
蛋白名称
Tropomyosin beta chain (Beta-tropomyosin) (Tropomyosin-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7169
Human Swissprot No.
P07951
Human Swissprot Link
https://www.uniprot.org/uniprot/P07951
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22004
Mouse Swissprot No.
P58774
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P58774/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=500450
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P58775/entry
特异性
This antibody detects endogenous levels of TPM2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Present in primary breast cancer tissue, absent from normal breast tissue.
细胞定位
Cytoplasm, cytoskeleton . Associates with F-actin stress fibers. .
功能
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization.
