产品名称
TPBG Rabbit Polyclonal Antibody
蛋白名称
Trophoblast glycoprotein (5T4 oncofetal antigen) (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (M6P1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7162
Human Swissprot No.
Q13641
Human Swissprot Link
https://www.uniprot.org/uniprot/Q13641
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21983
Mouse Swissprot No.
Q9Z0L0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z0L0/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83684
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5PQV5/entry
特异性
This antibody detects endogenous levels of TPBG at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
