产品名称
P3H1 Rabbit Polyclonal Antibody
基因名称
LEPRE1 GROS1 P3H1 PSEC0109
蛋白名称
Prolyl 3-hydroxylase 1 (EC 1.14.11.7) (Growth suppressor 1) (Leucine- and proline-enriched proteoglycan 1) (Leprecan-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64175
Human Swissprot No.
Q32P28
Human Swissprot Link
https://www.uniprot.org/uniprot/Q32P28
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56401
Mouse Swissprot No.
Q3V1T4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3V1T4/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=114200
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9R1J8/entry
特异性
This antibody detects endogenous levels of P3H1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
[Isoform 1]: Endoplasmic reticulum.; Secreted, extracellular space, extracellular matrix . Secreted into the extracellular matrix as a chondroitin sulfate proteoglycan (CSPG). .
功能
Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts.