产品名称
ENPP6 Rabbit Polyclonal Antibody
基因名称
ENPP6 UNQ1889/PRO4334
蛋白名称
Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (E-NPP 6) (NPP-6) (EC 3.1.4.-) (EC 3.1.4.38) (Choline-specific glycerophosphodiester phosphodiesterase) (Glycerophosphocholine cholinephosphodiesterase) [Cleaved into: Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 soluble form]
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=133121
Human Swissprot No.
Q6UWR7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q6UWR7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=320981
Mouse Swissprot No.
Q8BGN3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BGN3/entry
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/B0BND0/entry
特异性
This antibody detects endogenous levels of ENPP6 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Predominantly expressed in kidney and brain. In the kidney, expressed specifically in the proximal tubules and thin descending limbs of Henle (at protein level).
细胞定位
Cell membrane ; Lipid-anchor, GPI-anchor . A small amount of the protein may be found in the extracellular milieu.
功能
Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells . Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids (By similarity).
