产品名称
PHF15 Rabbit Polyclonal Antibody
基因名称
PHF15 JADE2 KIAA0239
蛋白名称
Protein Jade-2 (PHD finger protein 15)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23338
Human Swissprot No.
Q9NQC1
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NQC1
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=76901
Mouse Swissprot No.
Q6ZQF7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6ZQF7/entry
特异性
This antibody detects endogenous levels of PHF15 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity . Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A . Also acts as a ubiquitin ligase E3 toward itself. Positive regulator of neurogenesis (By similarity).
