产品名称
TMEM127 Rabbit Polyclonal Antibody
蛋白名称
Transmembrane protein 127
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55654
Human Swissprot No.
O75204
Human Swissprot Link
https://www.uniprot.org/uniprot/O75204
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=69470
Mouse Swissprot No.
Q8BGP5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BGP5/entry
特异性
This antibody detects endogenous levels of TMEM127 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cell membrane ; Multi-pass membrane protein . Cytoplasm . Association of TMEM127 with the cell membrane is enhanced by inhibition of endocytosis. In the cytoplasm, it colocalizes with markers of early endosomal structures, Golgi apparatus and lysosomes. .
功能
Controls cell proliferation acting as a negative regulator of TOR signaling pathway mediated by mTORC1. May act as a tumor suppressor.
