产品名称
ZFYVE21 Rabbit Polyclonal Antibody
蛋白名称
Zinc finger FYVE domain-containing protein 21 (ZF21)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79038
Human Swissprot No.
Q9BQ24
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9BQ24
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=68520
Mouse Swissprot No.
Q8VCM3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VCM3/entry
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/D3ZVP7/entry
特异性
This antibody detects endogenous levels of ZFYVE21 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cell junction, focal adhesion. Cytoplasmic vesicle. Endosome. Within cytoplasmic vesicles, partially colocalizes with EEA1, an endosomal marker.
功能
Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta-1/ITGB1 cell surface expression.
