产品名称
DEFA5 Rabbit Polyclonal Antibody
蛋白名称
Defensin-5 (Defensin, alpha 5) (HD5(20-94)) [Cleaved into: HD5(23-94); HD5(29-94); HD5(56-94); HD5(63-94)]
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1670
Human Swissprot No.
Q01523
Human Swissprot Link
https://www.uniprot.org/uniprot/Q01523
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P82106/entry
特异性
This antibody detects endogenous levels of DEFA5 at Human,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Paneth cells of the small intestine (at protein level).
细胞定位
Secreted . Cytoplasmic vesicle, secretory vesicle . Peptides HD5(20-94), HD5(23-94) and HD5(29-94) are found within tissues, HD5(20-94) being the predominant intracellular form. Peptides HD5(56-94) and HD5(63-94) are found in the extracellular milieu, HD5(63-94) being the most abundant form.
功能
Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.
