产品名称
WDFY4 Rabbit Polyclonal Antibody
基因名称
WDFY4 C10orf64 KIAA1607
蛋白名称
WD repeat- and FYVE domain-containing protein 4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57705
Human Swissprot No.
Q6ZS81
Human Swissprot Link
https://www.uniprot.org/uniprot/Q6ZS81
特异性
This antibody detects endogenous levels of WDFY4 at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Early endosome . Endoplasmic reticulum .
功能
Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy.